Aplysia : An activity book

 

The following activity book was created as part of my course assignment, which required creating an interactive learning tool. Through my activity book, I intend to simplify the papers written by Eric Kandel, who won the Nobel Prize in Medicine for his work investigating the neural correlates of learning mechanisms like habituation and sensitization. Kandel utilised Aplysia, a type of sea slug for his experiments because of its simple nervous system with large, easily identifiable neurons, making it ideal for investigating learning at the cellular level.

Due to time constraints, I have included only the following four papers in my book:

  • Pinsker, H., Kupfermann, I., Castellucci, V., & Kandel, E. R. (1970). Habituation and dishabituation of the gill-withdrawal reflex in Aplysia. Science, 167(3926), 1740-1742.

  • Kupfermann, I., Castellucci, V., Pinsker, H., & Kandel, E. R. (1970). Neuronal correlates of habituation and dishabituation of the gill-withdrawal reflex in Aplysia. Science, 167(3926), 1743-1745.

  • Castellucci, V., Pinsker, H., Kupfermann, I., & Kandel, E. R. (1970). Neuronal mechanisms of habituation and dishabituation of the gill-withdrawal reflex in Aplysia. Science, 167(3926), 1745-1748.

  • Castellucci, V. F., & Kandel, E. R. (1974). A quantal analysis of the synaptic depression underlying habituation of the gill-withdrawal reflex in Aplysia. Proceedings of the National Academy of Sciences, 71(12), 5004-5008.



References:

Image source: https://bonniekelso.com/2022/01/14/nudi-gill-pin-up-aplysia-californica/

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